recA mutants of E. coli K12: a personal turning point.

Abstract excerpt

A first year graduate student, Ann Dee Margulies, changed my research career in 1962 by challenging me to direct her in the isolation of recombination-deficient mutants of Escherichia coli K-12. She succeeded in isolating two mutants, which conjugated with donor strains and received the donor DNA, but could not recombine that DNA with their own chromosomes. Ann Dee showed that both mutants were much more...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Escherichia coli
• Share to Genes, Bacterial
• Share to Mutation