Article
Analysis of recA mutants with altered SOS functions.
Mutation research - 1 Jan 1995
Ennis D G, Levine A S, Koch W H, Woodgate R
Abstract excerpt
The Escherichia coli RecA protein has at least three roles in SOS mutagenesis: (1) derepression of the SOS regulon by mediating LexA cleavage; (2) activation of the UmuD mutagenesis protein by mediating its cleavage; and (3) targeting the Umu-like mutagenesis proteins to DNA. Using a combined approach of molecular and physiological assays, it is now possible to determine which of the three defined steps has been...
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