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Article

Analysis of recA mutants with altered SOS functions.

Mutation research - 1 Jan 1995

Ennis D G, Levine A S, Koch W H, Woodgate R

Abstract excerpt

The Escherichia coli RecA protein has at least three roles in SOS mutagenesis: (1) derepression of the SOS regulon by mediating LexA cleavage; (2) activation of the UmuD mutagenesis protein by mediating its cleavage; and (3) targeting the Umu-like mutagenesis proteins to DNA. Using a combined approach of molecular and physiological assays, it is now possible to determine which of the three defined steps has been...

Topics

Bacterial Proteins
Base Sequence
DNA-Directed DNA Polymerase
Escherichia coli Proteins
Molecular Sequence Data
Mutation
Rec A Recombinases
SOS Response, Genetics

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7528894
DOI: 10.1016/0921-8777(94)00045-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7528894-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Analysis of recA mutants with altered SOS functions.PMID 7528894Read ↗

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