Article
Genetic markers at the leptin (OB) locus are not significantly linked to hypertension in African Americans.
Hypertension (Dallas, Tex. : 1979) - 1 Jun 1998
Rutkowski M P, Klanke C A, Su Y R, Reif M, Menon A G
Abstract excerpt
Increased body mass index (BMI) has been correlated with increased blood pressure in human populations. To examine the role of the leptin gene (OB) in essential hypertension in African Americans, we performed affected sib pair analysis on a set of 103 hypertensive African American sibships using...
Topics
- Adipose Tissue
- Adult
- Black People
- Body Mass Index
- Data Interpretation, Statistical
- Exons
- Female
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Hypertension
- Leptin
- Male
- Middle Aged
- Obesity
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational