Markers for the gene ob and serum leptin levels in human morbid obesity.

doi:10.1007/s004390050406

Article

Markers for the gene ob and serum leptin levels in human morbid obesity.

Human genetics - 1 May 1997

Oksanen L, Ohman M, Heiman M, Kainulainen K, Kaprio J, Mustajoki P, Koivisto V, Koskenvuo M, Jänne O A, Peltonen L, Kontula K

Abstract excerpt

Leptin, the product of the ob gene, reduces body fat in genetically obese animals and circulates in elevated concentrations in the blood of obese patients. Polymorphic markers situated in the proximity of the human ob gene have recently been suggested to be linked to morbid obesity. We have studi...

Topics

Adult
Aged
Alleles
Blood Glucose
Body Mass Index
Female
Gene Frequency
Genetic Linkage
Genetic Markers
Humans
Insulin
Leptin
Lipids
Male
Microsatellite Repeats
Middle Aged
Nuclear Family
Obesity, Morbid

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