Article
Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7.
American journal of human genetics - 1 Sept 1996
Duggirala R, Stern M P, Mitchell B D, Reinhart L J, Shipman P A, Uresandi O C, Chung W K, Leibel R L, Hales C N, O'Connell P, Blangero J
Abstract excerpt
Despite the evidence that human obesity has strong genetic determinants, efforts at identifying specific genes that influence human obesity have largely been unsuccessful. Using the sibship data obtained from 32 low income Mexican American pedigrees ascertained on a type II diabetic proband and a multipoint variance-components method, we tested for linkage between various obesity-related traits plus associated...
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