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Article

Polymorphisms in the 3'UTR of the human leptin gene and their role in hypertension.

Molecular medicine reports - 1 Apr 2012

Akhter Qulsum, Masood Akbar, Ashraf Ruhi, Majid Sabia, Rasool Sabah, Khan Tanzeela, Rashid Tabasum, Sameer A Syed, Ganai Bashir Ahmad

Abstract excerpt

Leptin is a protein hormone, mainly synthesized in adipocytes, that regulates the food intake and energy expenditure of the body. Rare mutations in the leptin gene cause obesity. Common polymorphisms of the leptin gene have been associated with obesity, however their association with arterial blood pressure has not been fully elucidated. The aim of the present study was to examine the effect of variants in the 3'...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22218754
DOI: 10.3892/mmr.2012.743
PMCID: PMC3493089

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