Article
OB gene not linked to human obesity in Mexican American affected sib pairs from Starr County, Texas.
Human genetics - 1 Nov 1996
Bray M S, Boerwinkle E, Hanis C L
Abstract excerpt
Obesity is a highly prevalent disease, which is associated with a number of chronic conditions and, as such, represents a major public health burden. Numerous studies indicate that there is a genetic component contributing to interindividual variability in obesity. The discovery of the ob gene in mice, mutations in which produce extreme obesity and non-insulin-dependent diabetes mellitus (NIDDM), provides a prime...
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