Lack of association between an intronic polymorphism in the presenilin-1 gene and sporadic late-onset Alzheimer disease in Polish patients.

doi:10.1159/000017037

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Article

Lack of association between an intronic polymorphism in the presenilin-1 gene and sporadic late-onset Alzheimer disease in Polish patients.

Dementia and geriatric cognitive disorders - 1 Jan 2000

Kowalska A, Wender M, Lannfelt L

Abstract excerpt

The apolipoprotein E (APOE) gene has in many studies been identified as a susceptibility factor in Alzheimer's disease (AD). The APOE association is rather strong, but other not yet identified genetic factors are assumed to be involved in the pathogenesis of AD. Recently an association between an...

Topics

Age of Onset
Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Gene Frequency
Genotype
Humans
Introns
Membrane Proteins
Poland
Polymorphism, Genetic
Presenilin-1
Reference Values

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