Article
Presenilin-1 gene intronic polymorphism and late-onset Alzheimer's disease.
Journal of geriatric psychiatry and neurology - 1 Dec 2008
Dursun Erdinç, Gezen-Ak Duygu, Eker Engin, Ertan Turan, Engin Funda, Hanagasi Hasmet, Gürvit Hakan, Emre Murat, Yilmazer Selma
Abstract excerpt
Presenilin-1 is known to contribute to the pathogenesis of Alzheimer's disease. The association of an intronic polymorphism (rs165932) of the presenilin-1 gene with late-onset Alzheimer's disease has been documented. However, contradicting results have been shown in different populations. The aim of the current study is to determine whether there is an association between the intronic polymorphism of the...
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