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Article

Presenilin-1 gene intronic polymorphism in sporadic and familial Alzheimer's disease.

Neuroscience letters - 31 Jan 1997

Sorbi S, Nacmias B, Tedde A, Forleo P, Piacentini S, Latorraca S, Amaducci L

Abstract excerpt

A recent observation has shown a genetic association between an intronic polymorphism in the Presenilin-1 (PS-1) gene and late onset Alzheimer's disease (AD). The homozygosity of the 1 allele in the PS-1 gene was associated with a doubling of the risk for late onset AD. However, contrasting results have been published. We analyzed the distribution of the PS-1 intronic polymorphism in patients with sporadic AD and...

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PMID: 9111746
DOI: 10.1016/s0304-3940(97)13345-6

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Presenilin-1 gene intronic polymorphism in sporadic and familial Alzheimer's disease.PMID 9111746Read ↗

No association between an intronic polymorphism in the presenilin-1 gene and Alzheimer's disease.Semantic proximity Read ↗

Association between a PS-1 intronic polymorphism and late onset Alzheimer's disease.Semantic proximity Read ↗

Presenilin-1 polymorphism in Alzheimer's disease and vascular dementia.Semantic proximity Read ↗

Genetic association between intronic polymorphism in presenilin-1 gene and late-onset Alzheimer's disease. Alzheimer's Disease Collaborative Group.Semantic proximity Read ↗

No association between an intronic polymorphism in the presenilin-1 gene and Alzheimer disease in a German population.Semantic proximity Read ↗

F175S change and a novel polymorphism in presenilin-1 gene in late-onset familial Alzheimer's disease.Semantic proximity Read ↗

Complete analysis of the presenilin 1 gene in early onset Alzheimer's disease.Semantic proximity Read ↗

Presenilin-1 gene intronic polymorphism and late-onset Alzheimer's disease.Semantic proximity Read ↗

Genetic association of the presenilin-1 regulatory region with early-onset Alzheimer's disease in a population-based sample.Semantic proximity Read ↗

Case-control study of presenilin-1 intronic polymorphism in sporadic early and late onset Alzheimer's disease.Semantic proximity Read ↗

Association study and meta-analysis of Alzheimer's disease risk and presenilin-1 intronic polymorphism.Semantic proximity Read ↗

Presenilin-1 polymorphism in patients with Alzheimer's disease, vascular dementia and alcohol-associated dementia in Japanese population.Semantic proximity Read ↗

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