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Article

Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

Immunity - 1 May 1998

Zhang X, Sun S, Hwang I, Tough D F, Sprent J

Abstract excerpt

Proliferation of memory-phenotype (CD44hi) CD8+ cells induced by infectious agents can be mimicked by injection of type I interferon (IFN I) and by IFN I-inducing agents such as lipopolysaccharide and Poly I:C; such proliferation does not affect naive T cells and appears to be TCR independent. Since IFN I inhibits proliferation in vitro, IFN I-induced proliferation of CD8+ cells in vivo presumably occurs...

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PMID: 9620680
DOI: 10.1016/s1074-7613(00)80564-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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