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Article

MT-2 tropism and CCR-5 genotype strongly influence disease progression in HIV-1-infected individuals.

AIDS (London, England) - 7 May 1998

Bratt G, Leandersson A C, Albert J, Sandström E, Wahren B

Abstract excerpt

BACKGROUND: The beta-chemokine receptor CCR-5 is the coreceptor for cellular entry by non-syncytium-inducing (NSI) HIV-1 strains that dominate early in infection. A 32 base-pair deletion (delta32) in the CCR-5 gene renders this coreceptor non-functional. Heterozygosity for this deletion [delta32/wild-type (wt)] is associated with slow disease progression. The purpose of this study was to document the combined...

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Identifiers

PMID: 9619804
DOI: 10.1097/00002030-199807000-00009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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