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Article

Transcriptional interferences at the Hoxa4/Hoxa5 locus: importance of correct Hoxa5 expression for the proper specification of the axial skeleton.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 May 1998

Aubin J, Lemieux M, Tremblay M, Behringer R R, Jeannotte L

Abstract excerpt

We have previously described a Hoxa5 mutant mouse line in which specification of axial identity is perturbed and viability is markedly reduced. In the present study, we assay the Hoxa5 mutation in different genetic backgrounds and carry out a complete analysis of skeletal transformations. Althoug...

Topics

Animals
Bone Development
Cervical Vertebrae
DNA-Binding Proteins
Gene Expression Regulation, Developmental
Heterozygote
Homeodomain Proteins
Mice
Mice, Inbred C57BL
Mutation
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phosphoproteins

Thoracic Vertebrae

Transcription Factors

Transcription, Genetic

Source

Identifiers

PMID: 9603431
DOI: 10.1002/(SICI)1097-0177(199805)212:1<141::AID-AJA13>3.0.CO;2-A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9603431-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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