Cervical intraepithelial neoplasia III shows frequent allelic loss in 3p and 6p.

doi:10.1002/(sici)1098-2264(199805)22:1<57::aid-gcc8>3.0.co;2-6

Back to search

Article

Cervical intraepithelial neoplasia III shows frequent allelic loss in 3p and 6p.

Genes, chromosomes & cancer - 1 May 1998

Rader J S, Gerhard D S, O'Sullivan M J, Li Y, Li L, Liapis H, Huettner P C

Abstract excerpt

We have shown previously that a significant number of invasive cervical cancers (ICC) have nonrandom chromosomal losses in 3p, 6p, 11q, 2q, 6q, and 19q, thereby suggesting that genes involved in the suppression of tumor development or progression are located in these regions. Cervical intraepithe...

Topics

Adult
Alleles
Black People
Chromosomes, Human, Pair 3
Chromosomes, Human, Pair 6
Female
Humans
Loss of Heterozygosity
Middle Aged
Uterine Cervical Neoplasms
White People
Uterine Cervical Dysplasia

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.