Article
Cervical intraepithelial neoplasia III shows frequent allelic loss in 3p and 6p.
Genes, chromosomes & cancer - 1 May 1998
Rader J S, Gerhard D S, O'Sullivan M J, Li Y, Li L, Liapis H, Huettner P C
Abstract excerpt
We have shown previously that a significant number of invasive cervical cancers (ICC) have nonrandom chromosomal losses in 3p, 6p, 11q, 2q, 6q, and 19q, thereby suggesting that genes involved in the suppression of tumor development or progression are located in these regions. Cervical intraepithelial neoplasia (CIN) III is considered the precursor lesion for ICC of squamous type and occurs frequently with ICC of...
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