Article
Allelic losses at 3p and 11p are detected in both epithelial and stromal components of cervical small-cell neuroendocrine carcinoma.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Dec 2001
Man Y, Mannion C, Kuhls E, Moinfar F, Bratthauer G L, Albores-Saavedra J, Tavassoli F A
Abstract excerpt
Microdissected epithelial and stromal cells from 15 cervical small-cell carcinoma patients and 9 healthy control subjects were assessed for loss of heterozygosity with polymorphic DNA markers at chromosomes 3p and 11p. Among malignant lesions assessed with 7 markers at 3p, 21 allelic losses were detected from 193 informative samples. Of losses, 20 were in epithelial and 1 was in normal-appearing stromal cells....
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