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Article

PCR-RFLP studies on chromosome 3p in formaldehyde-fixed, paraffin-embedded cervical cancer tissues.

International journal of cancer - 15 Sept 1994

Karlsen F, Rabbitts P H, Sundresan V, Hagmar B

Abstract excerpt

Loss of heterozygosity (LOH) has been extensively studied on the short arm of chromosome 3, and functional proofs have been obtained defining a tumor-suppressor locus at 3p21-22. We examined 31 paraffin-embedded cervical cancer samples for LOH, using 5 PCR-primer pairs, located around 3p21. Allel...

Topics

Alleles
Base Sequence
Chromosomes, Human, Pair 3
DNA, Neoplasm
Female
Formaldehyde
Gene Deletion
Genetic Variation
Humans
Molecular Sequence Data
Paraffin Embedding
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Reproducibility of Results

Tissue Fixation

Uterine Cervical Neoplasms

Source

Identifiers

PMID: 7927869
DOI: 10.1002/ijc.2910580606

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7927869-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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PCR-RFLP studies on chromosome 3p in formaldehyde-fixed, paraffin-embedded cervical cancer tissues.PMID 7927869Read ↗

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