Article
High resolution analysis of chromosome 3p alterations in cervical carcinoma.
Cancer research - 15 Sept 1997
Larson A A, Kern S, Curtiss S, Gordon R, Cavenee W K, Hampton G M
Abstract excerpt
Although loss of heterozygosity (LOH) for loci on chromosome 3p is a common event in cervical carcinoma (CC), the frequency and affected regions of 3p are inconsistent among studies. Here we report a comprehensive analysis of LOH on 3p in 66 primary tumors and 16 CC-derived cell lines using a hig...
Topics
- Alleles
- Carcinoma
- Chromosome Mapping
- Chromosomes, Human, Pair 3
- Clone Cells
- DNA, Neoplasm
- Female
- Genetic Markers
- Heterozygote
- Humans
- Microsatellite Repeats
- Sequence Deletion
- Uterine Cervical Neoplasms