Article
High resolution analysis of chromosome 3p alterations in cervical carcinoma.
Cancer research - 15 Sept 1997
Larson A A, Kern S, Curtiss S, Gordon R, Cavenee W K, Hampton G M
Abstract excerpt
Although loss of heterozygosity (LOH) for loci on chromosome 3p is a common event in cervical carcinoma (CC), the frequency and affected regions of 3p are inconsistent among studies. Here we report a comprehensive analysis of LOH on 3p in 66 primary tumors and 16 CC-derived cell lines using a high density of marker loci. Clonal LOH was found in over 70% of primary tumors, and the patterns of loss indicated four...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
