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Article

HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 1998

Lee N, Goodlett D R, Ishitani A, Marquardt H, Geraghty D E

Abstract excerpt

Previous studies showed that HLA-E was expressed in lymphoblastoid cell line (LCL) 721.221 cells, but surface expression was lacking. To determine the signals controlling surface expression, we constructed a series of hybrid genes using complementary portions derived from the HLA-E and HLA-A2 genes. In this manner, a hybrid of HLA-E was identified, designated AEH, which differed from HLA-E by having the HLA-A2...

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PMID: 9590243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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