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Article

HLA-H: Transcriptional Activity and HLA-E Mobilization.

Frontiers in immunology - 1 Jan 2019

Jordier François, Gras Delphine, De Grandis Maria, D'Journo Xavier-Benoît, Thomas Pascal-Alexandre, Chanez Pascal, Picard Christophe, Chiaroni Jacques, Paganini Julien, Di Cristofaro Julie

Abstract excerpt

Little attention is paid to pseudogenes from the highly polymorphic HLA genetic region. The pseudogene HLA-H is defined as a non-functional gene because it is deleted at different frequencies in humans and because it encodes a potentially non-functional truncated protein. However, different studies have shown HLA-H transcriptional activity. We formerly identified 13 novel HLA-H alleles, including the H*02:07...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32010122
DOI: 10.3389/fimmu.2019.02986
PMCID: PMC6978722

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