Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-E surface expression is independent of the availability of HLA class I signal sequence-derived peptides in human tumor cell lines.

Human immunology - 1 Jan 2005

Palmisano Giulio Lelio, Contardi Elisabetta, Morabito Anna, Gargaglione Vittoria, Ferrara Giovanni Battista, Pistillo Maria Pia

Abstract excerpt

Human leukocyte antigen (HLA)-E is a nonclassic HLA class I molecule whose expression at the cell surface of tumor cells might allow them to escape T- and natural killer (NK)-cell immune surveillance. In this study, we analyzed HLA-E expression in a panel of human HLA-typed tumor cell lines of different histotypes by flow cytometry with anti-HLA-E monoclonal antibodies and by reverse transcriptase-polymerase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiporters
Share to ATP Binding Cassette Transporter, Subfamily B, Member 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caco-2 Cells

Share to Histocompatibility Antigens Class I

Share to HLA-E Antigens

Share to HT29 Cells

Share to Immunoglobulins

Share to Protein Sorting Signals

Source

Identifiers

PMID: 15620456
DOI: 10.1016/j.humimm.2004.10.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-E surface expression is independent of the availability of HLA class I signal sequence-derived peptides in human tumor cell lines.PMID 15620456Read ↗

Analysis of HLA-E expression in human tumors.Semantic proximity Read ↗

TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide.Semantic proximity Read ↗

HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences.Semantic proximity Read ↗

Human leukocyte antigen-E alleles and expression in patients with serous ovarian cancer.Semantic proximity Read ↗

Peptide-induced HLA-E expression in human PBMCs is dependent on peptide sequence and the HLA-E genotype.Semantic proximity Read ↗

HLA-E allelic genotype correlates with HLA-E plasma levels and predicts early progression in chronic lymphocytic leukemia.Semantic proximity Read ↗

Cell surface expression level variation between two common Human Leukocyte Antigen alleles, HLA-A2 and HLA-B8, is dependent on the structure of the C terminal part of the alpha 2 and the alpha 3 domains.Semantic proximity Read ↗

Impact of HLA-E gene polymorphism on HLA-E expression in tumor cells and prognosis in patients with stage III colorectal cancer.Semantic proximity Read ↗

Markedly decreased expression of TAP1 and LMP2 genes in HLA class I-deficient human tumor cell linesSemantic proximity Read ↗

HLA-E contributes to an immune-inhibitory phenotype of glioblastoma stem-like cells.Semantic proximity Read ↗

High expression of HLA-E in colorectal carcinoma is associated with a favorable prognosis.Semantic proximity Read ↗

Expression of Endoplasmic Reticulum Aminopeptidases in EBV-B Cell Lines from Healthy Donors and in Leukemia/Lymphoma, Carcinoma, and Melanoma Cell LinesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.