Article
Peptide-induced HLA-E expression in human PBMCs is dependent on peptide sequence and the HLA-E genotype.
Tissue antigens - 1 Apr 2015
Lauterbach N, Wieten L, Popeijus H E, Vanderlocht J, van Zon P M H, Voorter C E M, Tilanus M G J
Abstract excerpt
Human Leukocyte Antigen (HLA)-E is a low-polymorphic non-classical HLA class I molecule which plays a crucial role in immune surveillance by presentation of peptides to T and natural killer (NK) cells. HLA-E polymorphism is related to HLA-E surface expression and is associated with patient outcome after stem cell transplantation. We aim to investigate the regulation of HLA-E expression level in peripheral blood...
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