Article
Expression of HLA class I antigens in transporter associated with antigen processing (TAP)-deficient mutant cell lines.
Tissue antigens - 1 Oct 1998
Young N T, Mulder A, Cerundolo V, Claas F H, Welsh K I
Abstract excerpt
Cells lacking expression of the transporter associated with antigen processing (TAP) are deficient in surface HLA class I, yet express reduced levels of HLA-A2 antigen through TAP-independent processing pathways. We have analysed the expression of HLA-A, -B and -C antigens on the 721.174 and T2 TAP-deficient mutant cell lines using a panel of monoclonal antibodies specific for the HLA antigens encoded by the...
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