Article
Allele-specific differences in the interaction of MHC class I molecules with transporters associated with antigen processing.
Journal of immunology (Baltimore, Md. : 1950) - 1 May 1996
Neisig A, Wubbolts R, Zang X, Melief C, Neefjes J
Abstract excerpt
MHC class I molecules bind peptides that are translocated from the cytosol into the endoplasmic reticulum by the peptide transporter associated with antigen processing (TAP). Class I heterodimers have been shown to associate with TAP and are released when loaded with peptide. Here, we show the ex...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP-Binding Cassette Transporters
- Alleles
- Amino Acid Sequence
- Animals
- Antigen Presentation
- Biological Transport
- HLA Antigens
- Histocompatibility Antigens Class I
- Humans
- Molecular Sequence Data
- Rabbits