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Article

Allele-specific differences in the interaction of MHC class I molecules with transporters associated with antigen processing.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 1996

Neisig A, Wubbolts R, Zang X, Melief C, Neefjes J

Abstract excerpt

MHC class I molecules bind peptides that are translocated from the cytosol into the endoplasmic reticulum by the peptide transporter associated with antigen processing (TAP). Class I heterodimers have been shown to associate with TAP and are released when loaded with peptide. Here, we show the existence of two pools of class I heterodimers, one associated with TAP and one that is free. Whereas the free pool is...

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Source

Identifiers

PMID: 8617941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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