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Article

HLA-E: strong association with beta2-microglobulin and surface expression in the absence of HLA class I signal sequence-derived peptides.

Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 2008

Lo Monaco Elisa, Sibilio Leonardo, Melucci Elisa, Tremante Elisa, Suchànek Miloslav, Horejsi Vaclav, Martayan Aline, Giacomini Patrizio

Abstract excerpt

The nonclassical class I HLA-E molecule folds in the presence of peptide ligands donated by the signal sequences of permissive class I HLA alleles, with the aid of TAP and tapasin. To identify HLA-E-specific Abs, four monoclonals of the previously described MEM series were screened by isoelectric focusing (IEF) blot and immunoprecipitation/IEF on >30 single-allele class I transfectants and HLA-homozygous B...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18832701
DOI: 10.4049/jimmunol.181.8.5442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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