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Article

Polymorphism within the HLA-DQB1*02 promoter associated with susceptibility to coeliac disease.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Feb 1998

Fernandez-Arquero M, Caldés T, Casado E, Maluenda C, Figueredo M A, De La Concha E G

Abstract excerpt

Susceptibility to coeliac disease is associated with a particular HLA-DQ alpha beta heterodimer encoded by the DQA1*0501 and DQB1*02 genes. A single base polymorphism in the DQB1*02 promoter region in DR7, DQA1*0201, DQB1*02 haplotypes was observed, associated with an increased susceptibility to the disease. This finding suggests a novel mechanism of susceptibility to immune-mediated diseases.

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Source

Identifiers

PMID: 9587738
DOI: 10.1046/j.1365-2370.1998.00083.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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