Article
On the HLA-DQ(alpha 1*0501, beta 1*0201)-associated susceptibility in celiac disease: a possible gene dosage effect of DQB1*0201.
Tissue antigens - 1 Apr 1993
Ploski R, Ek J, Thorsby E, Sollid L M
Abstract excerpt
The HLA-associated susceptibility to develop celiac disease (CD) seems mainly to be conferred by a particular HLA-DQ heterodimer encoded by the DQA1*0501 and DQB1*0201 genes either in cis or in trans position. To study the possible influence of DRB1 or other DQA1 and DQB1 alleles on the CD susceptibility conferred by these DQ genes, we performed genomic HLA typing of 94 CD patients, selected those who carried at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
