Article
On the HLA-DQ(alpha 1*0501, beta 1*0201)-associated susceptibility in celiac disease: a possible gene dosage effect of DQB1*0201.
Tissue antigens - 1 Apr 1993
Ploski R, Ek J, Thorsby E, Sollid L M
Abstract excerpt
The HLA-associated susceptibility to develop celiac disease (CD) seems mainly to be conferred by a particular HLA-DQ heterodimer encoded by the DQA1*0501 and DQB1*0201 genes either in cis or in trans position. To study the possible influence of DRB1 or other DQA1 and DQB1 alleles on the CD suscep...
Topics
- Alleles
- Base Sequence
- Celiac Disease
- DNA
- Disease Susceptibility
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Haplotypes
- Histocompatibility Antigens Class II
- Homozygote
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction
- Registries