Article
Reevaluation of the relative risk for susceptibility to celiac disease of HLA-DRB1, -DQA1, -DQB1, -DPB1, and -TAP2 alleles in a French population.
Human immunology - 1 Jul 1995
Meddeb-Garnaoui A, Zeliszewski D, Mougenot J F, Djilali-Saiah I, Caillat-Zucman S, Dormoy A, Gaudebout C, Tongio M M, Baudon J J, Sterkers G
Abstract excerpt
In a population of 46 children with CD recruited in the Paris area of France, an excess of DRB1*03 and DRB1*07 alleles and of DR3/DR7, DR3/DR3 and DR11(or 12)/DR7 phenotypes was found (RRs of 6.3, 9.3, 24.6, 15, and 15.1, respectively), which is reminiscent of the markers of susceptibility observed in southern rather than in northern European celiac patients. More importantly, the highest association with CD was...
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