Article
Associations between alleles of the major histocompatibility complex-encoded ABC transporter gene TAP2, HLA class II alleles, and celiac disease susceptibility.
Human immunology - 1 Jan 1994
Tighe M R, Hall M A, Cardi E, Ashkenazi A, Lanchbury J S, Ciclitira P J
Abstract excerpt
The study of celiac disease among Southern European populations has confirmed the hypothesis from Northern Europe that a close association exists between disease susceptibility and a combination of polymorphic alleles at the HLA-DQ loci (DQA1*0501-DQB1*0201) arranged either in a cis- or a trans-c...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Adolescent
- Adult
- Aged
- Alleles
- Base Sequence
- Biological Transport
- Carrier Proteins
- Celiac Disease
- Cell Line
- Child
- Child, Preschool
- DNA Primers
- Disease Susceptibility
- HLA-DQ Antigens
- HLA-DR Antigens
- Humans