Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-DQA10501 and DQB102 homozygosity and disease susceptibility in Spanish coeliac patients.

Experimental and clinical immunogenetics - 1 Jan 1997

Arranz E, Telleria J J, Sanz A, Martin J F, Alonso M, Calvo C, Blanco-Quirós A

Abstract excerpt

Coeliac disease (CD) susceptibility is strongly associated with HLA-DQA1*0501 and DQB1*02 alleles. There are discordant reports on whether homozygosity increases the risk. We genotyped HLA-DQA1*0501 and DQB1*02 in 50 CD patients, 100 parents, and 50 controls. Most patients (96%) were positive for DQA1*0501 (RR = 18.07, p < 0.001), 94% for DQB1*02 (RR = 17.55, p < 0.001), and 92% for both alleles together (RR =...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Child, Preschool
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to HLA-DQ alpha-Chains

Share to HLA-DQ Antigens

Share to HLA-DQ beta-Chains

Share to Homozygote

Source

Identifiers

PMID: 9523165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-DQA1*0501 and DQB1*02 homozygosity and disease susceptibility in Spanish coeliac patients.PMID 9523165Read ↗

Allele and haplotype frequencies for HLA class II (DQA1 and DQB1) loci in patients with celiac disease from Spain.Semantic proximity Read ↗

HLA-DQ and risk gradient for celiac disease.Semantic proximity Read ↗

HLA class II high-resolution genotyping in Greek children with celiac disease and impact on disease susceptibility.Semantic proximity Read ↗

Risk variation in celiac disease in a population from Southern Spain: evaluating the influence of the DQB1*02:02 allele frequency.Semantic proximity Read ↗

Celiac disease and HLA-DQ genotype: diagnosis of different genetic risk profiles related to the age in Badajoz, southwestern Spain.Semantic proximity Read ↗

Carrier frequency of HLA-DQB1*02 allele in patients affected with celiac disease: A systematic review assessing the potential rationale of a targeted allelic genotyping as a first-line screening.Semantic proximity Read ↗

HLA-DQA1 and HLA-DQB1 in Celiac disease predisposition: practical implications of the HLA molecular typing.Semantic proximity Read ↗

HLA-DQ relative risks for coeliac disease in European populations: a study of the European Genetics Cluster on Coeliac Disease.Semantic proximity Read ↗

The involvement of the HLA-DQB1 alleles in the risk and the severity of Iranian coeliac disease patients.Semantic proximity Read ↗

HLA genotyping in pediatric celiac disease patients.Semantic proximity Read ↗

Genetic susceptibilty and celiac disease: what role do HLA haplotypes play?Semantic proximity Read ↗

HLA-DQ distribution and risk assessment of celiac disease in a Spanish center.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.