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Article

Response to platelet-derived growth factor by phenotypically different cultured human aortic smooth muscle cells.

Biochemistry and molecular biology international - 1 Apr 1998

Kato M, Tanimoto A, Arima N, Morimatsu M, Sasaguri Y

Abstract excerpt

We investigated the effects of PDGF on DNA synthesis and mitogen-activated protein (MAP) kinase activity, and demonstrated that the adult intimal SMC was concentration-dependently stimulated by all PDGF isoforms in terms of both [3H]thymidine incorporation and MAP kinase activation, with PDGF-BB and -AB being more potent than PDGF-AA. The intimal SMCs and the neonatal SMCs showed a similar response with regard to...

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Identifiers

PMID: 9584995
DOI: 10.1080/15216549800201862

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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