Article
Expression of PDGF alpha- and beta-receptors in rat arterial smooth muscle cells is phenotype and growth state dependent.
Growth factors (Chur, Switzerland) - 1 Jan 1990
Sjölund M, Rahm M, Claesson-Welsh L, Sejersen T, Heldin C H, Thyberg J
Abstract excerpt
Adult rat arterial smooth muscle cells were shown to express mRNA for the platelet-derived growth factor (PDGF) alpha- and beta-receptors and to bind radioiodinated PDGF-AA and PDGF-BB in a phenotype-dependent and growth state-dependent manner. PDGF alpha-receptor mRNA was not detected in the int...
Topics
- Animals
- Aorta
- Cell Division
- DNA
- Gene Expression
- Male
- Muscle, Smooth, Vascular
- Phenotype
- Platelet-Derived Growth Factor
- RNA, Messenger
- Rats
- Rats, Inbred Strains
- Receptors, Cell Surface
- Receptors, Platelet-Derived Growth Factor