Article
Plasminogen activator expression in rat arterial smooth muscle cells depends on their phenotype and is modulated by cytokines.
Circulation research - 1 Jun 1998
Bochaton-Piallat M L, Gabbiani G, Pepper M S
Abstract excerpt
Cultured rat aortic smooth muscle cells (SMCs) exhibit at least 2 phenotypic variants: (1) a spindle-shaped phenotype, obtained from normal adult media, and (2) an epithelioid phenotype, obtained from intimal thickening 15 days after endothelial injury. Both phenotypes can be cloned from each location, with normal media yielding a majority of spindle-shaped clones and intimal thickening yielding a majority of...
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