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Article

Phenotypic changes of human aortic smooth muscle cells during development and in the adult vessel.

The American journal of physiology - 1 Oct 1991

Glukhova M A, Frid M G, Koteliansky V E

Abstract excerpt

To characterize phenotypic expression of human aortic smooth muscle cells (SMCs), we have studied the content of cytodifferentiation-related cytoskeletal proteins, and of fibronectin (FN) variants in the samples of media from the fetal, child, and adult aorta and in the subendothelial intima of the normal and atherosclerotic aorta. Mature SMCs from the adult aortic media contained high amounts of alpha-SM-actin,...

Topics

Adult
Aging
Aorta
Arteriosclerosis
Biomarkers
Cell Differentiation
Contractile Proteins
Cytoskeletal Proteins
Embryonic and Fetal Development
Fibronectins
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Infant

Muscle, Smooth, Vascular

Phenotype

Source

Identifiers

PMID: 1928456
DOI: 10.1152/ajpheart.1991.261.4.78

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1928456-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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