No p16INK4A/CDKN2/MTS1 mutations independent of p53 status in soft tissue sarcomas.

doi:10.1002/(SICI)1096-9896(199801)184:1<14::AID-PATH957>3.0.CO;2-K

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Article

No p16INK4A/CDKN2/MTS1 mutations independent of p53 status in soft tissue sarcomas.

The Journal of pathology - 1 Jan 1998

Meye A, Würl P, Hinze R, Berger D, Bache M, Schmidt H, Rath F W, Taubert H

Abstract excerpt

The p16INK4A/CDKN2/MTS1 gene encodes a specific inhibitor of cyclin-dependent kinases (CDKs) 4 and 6. This study investigates p16INK4A gene status and expression in mesenchymal tumours, in particular soft tissue sarcomas (STSs). Employing non-radioactive polymerase chain reaction-single strand co...

Topics

Cyclin-Dependent Kinases
Genes, p16
Genes, p53
Humans
Mutation
Neoplasm Proteins
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Retinoblastoma Protein
Sarcoma
Soft Tissue Neoplasms

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