Article
Aberrant expression of cell-cycle regulatory proteins in human mesenchymal neoplasia.
Cancer detection and prevention - 1 Jan 2001
Creager A J, Cohen J A, Geradts J
Abstract excerpt
We previously demonstrated that approximately one-half of soft-tissue sarcomas were devoid of either pRB, the product of the retinoblastoma gene, or 16, the product of the MTS1/CDKN2 gene, while a smaller subset of aggressive mesenchymal tumors without metastatic potential did not express RB by immunohistochemistry. We now studied the expression of two additional important cell-cycle regulators, namely cyclin D1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
