Article
[Frequency, distribution and prognostic relevance of p53 mutations in soft tissue sarcomas].
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 1998
Taubert H, Würl P, Meye A, Bache M, Kroll J, Lautenschläger C, Thamm B, Holzhausen H J, Hinze R, Schmidt H, Berger D, Rath F W
Abstract excerpt
Soft tissue sarcomas although rarely occurring (about 1% of malignant tumors), are because of their histo-morphological diversity and often similar appearance to tumor-like lesions difficult to characterize and estimate in their tumor biological behaviour. Analysis of molecular characteristics as alterations in tumor-suppressor and oncogenes may allow insight in STS genesis. We have chosen the in carcinomas well,...
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