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Article

Gene alterations at the CDKN2A (p16/MTS1) locus in soft tissue tumors.

International journal of oncology - 1 Aug 1998

Schneider-Stock R, Walter H, Haeckel C, Radig K, Rys J, Roessner A

Abstract excerpt

The CDKN2A gene (p16/MTS1) is a tumor suppressor that is frequently deleted, mutated, or inactivated by transcriptional silencing in certain tumor types and many tumor cell lines. We analyzed CDKN2A gene mutations and the frequency of loss of heterozygosity (LOH) at the CDKN2A locus in 135 soft t...

Topics

Alleles
Exons
Gene Deletion
Genes, p16
Humans
Loss of Heterozygosity
Microsatellite Repeats
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
RNA Splicing
Soft Tissue Neoplasms

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Identifiers

PMID: 9664128
DOI: 10.3892/ijo.13.2.325

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9664128-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Gene alterations at the CDKN2A (p16/MTS1) locus in soft tissue tumors.PMID 9664128Read ↗

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