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Article

Determinants of slow gating in ClC-0, the voltage-gated chloride channel of Torpedo marmorata.

The American journal of physiology - 1 Apr 1998

Fong P, Rehfeldt A, Jentsch T J

Abstract excerpt

Membrane hyperpolarization normally activates the slow gate of the Torpedo voltage-gated chloride channel (ClC-0). To elucidate the structural basis of this process, carboxy terminus truncation mutants and chimeras were constructed, expressed in Xenopus oocytes, and evaluated using a two-microele...

Topics

Animals
Chimera
Chloride Channels
Chromosome Mapping
Codon
Electrophysiology
Female
Ion Channel Gating
Mutation
Oocytes
Torpedo
Xenopus laevis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 9575793
DOI: 10.1152/ajpcell.1998.274.4.C966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9575793-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Determinants of slow gating in ClC-0, the voltage-gated chloride channel of Torpedo marmorata.PMID 9575793Read ↗

Analysis of a protein region involved in permeation and gating of the voltage-gated Torpedo chloride channel ClC-0.Semantic proximity Read ↗

Two physically distinct pores in the dimeric ClC-0 chloride channel.Semantic proximity Read ↗

Temperature dependence of fast and slow gating relaxations of ClC-0 chloride channels.Semantic proximity Read ↗

Removal of gating in voltage-dependent ClC-2 chloride channel by point mutations affecting the pore and C-terminus CBS-2 domain.Semantic proximity Read ↗

Insights into CLC-0's Slow-Gating from Intracellular Proton Inhibition.Semantic proximity Read ↗

Intracellular proton regulation of ClC-0.Semantic proximity Read ↗

The myotonia congenita mutation A331T confers a novel hyperpolarization-activated gate to the muscle chloride channel ClC-1.Semantic proximity Read ↗

Gating of the voltage-dependent chloride channel CIC-0 by the permeant anion.Semantic proximity Read ↗

Drastic reduction of the slow gate of human muscle chloride channel (ClC-1) by mutation C277S.Semantic proximity Read ↗

Proton-dependent inhibition, inverted voltage activation, and slow gating of CLC-0 Chloride Channel.Semantic proximity Read ↗

The role of protons in fast and slow gating of the Torpedo chloride channel ClC-0.Semantic proximity Read ↗

Inward rectification in ClC-0 chloride channels caused by mutations in several protein regions.Semantic proximity Read ↗

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