Article
Inward rectification in ClC-0 chloride channels caused by mutations in several protein regions.
The Journal of general physiology - 1 Aug 1997
Ludewig U, Jentsch T J, Pusch M
Abstract excerpt
Several cloned ClC-type Cl- channels open and close in a voltage-dependent manner. The Torpedo electric organ Cl- channel, ClC-0, is the best studied member of this gene family. ClC-0 is gated by a fast and a slow gating mechanism of opposite voltage direction. Fast gating is dependent on voltage...
Topics
- Amino Acid Sequence
- Animals
- Chloride Channels
- Electric Organ
- Electric Stimulation
- Electrophysiology
- Ion Channel Gating
- Membrane Potentials
- Molecular Sequence Data
- Mutation
- Oocytes
- Patch-Clamp Techniques
- Perchlorates
- Phenotype
- Polymerase Chain Reaction
- Torpedo