Gating of the voltage-dependent chloride channel CIC-0 by the permeant anion.

doi:10.1038/373527a0

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Article

Gating of the voltage-dependent chloride channel CIC-0 by the permeant anion.

Nature - 9 Feb 1995

Pusch M, Ludewig U, Rehfeldt A, Jentsch T J

Abstract excerpt

Chloride channels of the ClC family are important for the control of membrane excitability, cell volume regulation, and possibly transepithelial transport. Although lacking the typical voltage-sensor found in cation channels, gating of ClC channels is clearly voltage-dependent. For the prototype...

Topics

Animals
Cells, Cultured
Chloride Channels
Chlorides
Electrophysiology
Ion Channel Gating
Mutation
Oocytes
Recombinant Proteins
Torpedo
Xenopus

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