Article
Two physically distinct pores in the dimeric ClC-0 chloride channel.
Nature - 26 Sept 1996
Ludewig U, Pusch M, Jentsch T J
Abstract excerpt
The Torpedo chloride channel ClC-0 is the prototype of a large family of chloride channels that have roles in transepithelial transport and in regulating electrical excitability and cell volume. ClC-0 opens in bursts with two identical conductance levels of approximately 8pS. Hyperpolarization sl...
Topics
- 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
- Amino Acid Sequence
- Animals
- Chloride Channels
- Electrochemistry
- Ion Channel Gating
- Kinetics
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Recombinant Proteins
- Torpedo
- Xenopus