Article
Absence of an association between mannose-binding lectin polymorphism and rheumatoid arthritis.
British journal of rheumatology - 1 Feb 1998
Stanworth S J, Donn R P, Hassall A, Dawes P, Ollier W, Snowden N
Abstract excerpt
It has been proposed that mannose-binding lectin (MBL) interactions with agalactosyl forms of IgG immunoglobulins found in rheumatoid synovial fluid might lead to enhanced complement activation, an important mediator of the joint damage in rheumatoid arthritis (RA). In order to investigate this possible link between increased MBL-mediated activation of complement and perpetuation of rheumatoid synovitis, we have...
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