Article
Mannose-binding lectin polymorphisms are not associated with rheumatoid arthritis--confirmation in two large cohorts.
Rheumatology (Oxford, England) - 1 Aug 2008
van de Geijn F E, Hazes J M W, Geleijns K, Emonts M, Jacobs B C, Dufour-van den Goorbergh B C M, Dolhain R J E M
Abstract excerpt
OBJECTIVES: In RA, conflicting results have been described on the association between genotypes of the complement factor mannose-binding lectin (MBL) and disease susceptibility and severity. This might be due to underpowerment of previous research work and the fact that no confirmation cohorts were used. Therefore a different approach is warranted. METHODS: MBL2 gene polymorphisms were determined in two RA...
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