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Article

Mannose-binding lectin gene polymorphisms in Brazilian patients with rheumatoid arthritis.

The Journal of rheumatology - 1 Jan 2012

Martiny Fernanda Leticia, Veit Tiago Degani, Brenol Claiton Viegas, Brenol João Carlos Tavares, Xavier Ricardo Machado, Bogo Maurício Reis, Chies José Artur Bogo

Abstract excerpt

OBJECTIVE: Rheumatoid arthritis (RA) is a disease with unknown etiology but it is probably multifactorial. RA susceptibility is related to genetic, hormonal, immunologic, and environmental factors. Mannose-binding lectin (MBL) is an important protein of the human innate immune system, encoded by the MBL2 gene. Polymorphisms in MBL2 were associated with several diseases, and may be an important factor in RA...

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Source

Identifiers

PMID: 22002015
DOI: 10.3899/jrheum.110052

Genes

MBL2

Provenance

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