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Mannose-binding lectin and rheumatoid arthritis in Southern Chinese

1 Aug 2000

Abstract excerpt

OBJECTIVE: Insufficiency of mannose-binding lectin (MBL) is associated with recurrent infections. Rheumatoid arthritis (RA) may represent an aberrant immune response to infections. This study examined the phenotypic expression and variant alleles of the MBL gene and its etiologic role in Chinese with RA. METHODS: We studied 211 RA patients and 196 healthy subjects. Serum MBL concentrations and codon-54 mutation...

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PMID: 10943857
DOI: 10.1002/1529-0131(200008)43:8<1679::aid-anr3>3.0.co;2-d

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