Article
The influence of mannose binding lectin polymorphisms on disease outcome in early polyarthritis. TIRA Group.
The Journal of rheumatology - 1 May 2001
Jacobsen S, Madsen H O, Klarlund M, Jensen T, Skjødt H, Jensen K E, Svejgaard A, Garred P
Abstract excerpt
OBJECTIVE: To determine whether variant alleles of the mannose binding lectin (MBL) gene causing low serum concentrations of MBL are associated with increased susceptibility to rheumatoid arthritis (RA) and erosive outcome in an inception cohort of patients with early polyarthritis. METHODS: MBL and HLA-DRB1 alleles were determined by polymerase chain reaction in 68 Danish patients with incident early...
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