Article
Mannose-Binding Lectin Gene Variants as Disease Susceptibility Biomarkers in Rheumatoid Arthritis.
Genetic testing and molecular biomarkers - 1 Sept 2024
Kaur Tarnjeet, Kashyap Shreya Singh, Arora Sumeet, Singh Jatinder, Kaur Manpreet
Abstract excerpt
Background: Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disease characterized by progressive destruction of peripheral joints. About 1% of the human population worldwide is suffering from this disease. The pathophysiology of RA is largely being influenced by immune dysregulation. Mannose-binding lectin (MBL), an acute-phase protein, has been reported to play an important role in pathogenesis...
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