Article
Lectin pathway factors in patients suffering from juvenile idiopathic arthritis.
Immunology and cell biology - 1 Sept 2017
Kasperkiewicz Katarzyna, Eppa Łukasz, Świerzko Anna S, Bartłomiejczyk Marcin A, Żuber Zbigniew M, Siniewicz-Luzeńczyk Katarzyna, Mężyk Elżbieta, Matsushita Misao, Bąk-Romaniszyn Leokadia, Zeman Krzysztof, Skurnik Mikael, Cedzyński Maciej
Abstract excerpt
Both complement activation and certain infections (including those with Yersinia sp.) may contribute to the pathogenesis of juvenile idiopathic arthritis (JIA). We investigated factors specific for the lectin pathway of complement: mannose-binding lectin (MBL), ficolins and MBL-associated serine protease-2 (MASP-2), in 144 patients and 98 controls. One hundred and six patients had oligoarticular disease and 38...
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