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Article

Mannose-binding lectin polymorphisms and rheumatoid arthritis: A short review and meta-analysis.

Molecular immunology - 1 Jan 2016

Epp Boschmann Stefanie, Goeldner Isabela, Tuon Felipe Francisco, Schiel Wagner, Aoyama Fernanda, de Messias-Reason Iara J

Abstract excerpt

Mannose-binding lectin (MBL) is a pattern recognition receptor of the lectin pathway of complement system. MBL binds to carbohydrates on microorganism's surfaces leading to complement activation, opsonization and phagocytosis. Polymorphisms in the MBL gene (MBL2) are associated with variations on MBL serum levels and with the susceptibility to various infectious and autoimmune diseases. The involvement of the...

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Source

Identifiers

PMID: 26608926
DOI: 10.1016/j.molimm.2015.10.010

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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