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Article

Activities of SV40 T antigen necessary for the induction of tetraploid DNA content in permissive CV-1 cells.

Cytometry - 1 Apr 1998

Perry M B, Lehman J M

Abstract excerpt

To determine the role of SV40 T antigen in stimulating multiple rounds of DNA synthesis in permissive cells, CV-1 cells were transfected with plasmids expressing mutant or wt T antigen in the presence or absence of the SV40 origin of replication. Induction of cells with > G2 DNA content (tetraploid DNA content) and levels of T antigen protein were detected and analyzed by flow cytometry. The mutant T antigen...

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PMID: 9551600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Activities of SV40 T antigen necessary for the induction of tetraploid DNA content in permissive CV-1 cells.PMID 9551600Read ↗

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